Custom-designed PTFE, PFA, and FEP hoses for fluid systems, bearing and cooling systems, and more!
Do you have highly sensitive, ultra-pure, chemically demanding, and thermally stressed processes in biopharmaceuticals or pharmaceutical development? We offer precision-engineered, certified PTFE, PFA, and FEP tubing as safe connection systems.
Biopharmaceuticals & Chemistry - High-Performance PTFE and PFA Tubing
Fluid systems, storage, and cooling systems for the biopharmaceutical industry
When highly sensitive media must be safely conveyed, stored, temperature-controlled, or dispensed, the quality of the hose solution determines process stability, product protection, and system reliability. This is precisely where FEP, PTFE, and PFA hoses, for example, demonstrate their strengths: in applications where chemical resistance, high purity, and robust material performance are essential. For the biopharmaceutical industry, pharmaceutical development, or storage and cooling systems, the Masterflex Group offers high-performance hose systems that can be precisely tailored to the handling of sensitive media and complex system requirements. This results in connection solutions that effectively combine safety, flexibility, and regulatory compliance in a demanding industrial environment.
High-purity PFA hose solutions made from raw material-certified fluoropolymers offer a chemically inert, low-contamination, and process-stable alternative to traditional stainless steel pipe systems and fittings. Masterflex Group develops ultra-high-purity, high-performance biopharmaceutical PTFE and PFA tubing specifically designed to meet the requirements of modern biotech and pharmaceutical facilities.
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PTFE and PFA tubing is manufactured in Germany under ultra-high-purity conditions—reliably, precisely, and, upon request, fully customized.
Fluoropolymer Solutions Catalog
PTFE and PFA Hoses for Conveying Metal-Sensitive Substances
Safe Plastic Hoses for Conveying Metal-Sensitive Substances
When handling metal-sensitive substances, maximum media compatibility and a particularly inert material base are essential. PTFE and PFA hoses support safe and gentle media handling in these applications because they can be designed for high-purity and sensitive substances and minimize the risk of undesirable interactions in the process. In the chemical and pharmaceutical industries, certified raw materials such as Teflon™ and COAs are a given for us. We are distinguished by our in-depth understanding of biopharmaceutical and biotechnological applications and our close collaboration with OEMs and end users throughout the entire product lifecycle.
Storage and Cooling Systems in the Pharmaceutical Industry
Fluid Transfer for Storage and Cooling Systems in the Pharmaceutical Industry
In storage and cooling systems used in the pharmaceutical industry, liquids and sensitive media often need to be transported stably under constant temperature conditions. PTFE and PFA hoses for the chemical and pharmaceutical industries offer a robust solution when chemical resistance, temperature tolerance, and long-term process reliability are required in cooling or supply systems. For tight installation spaces or specialized applications, we design and manufacture customized solutions for you.
FEP Tubing – for Chemical and Pharmaceutical Applications
Safe Media Handling with High-Performance FEP Hoses
FEP hoses from the Masterflex Group are ideal for applications in which chemical and pharmaceutical media need to be transported safely, transparently, and in a controlled manner. They offer advantages in process monitoring, flexible integration into systems, and media handling that requires clean, stable handling.
Connection of Filter Units and Ventilation Systems
Advantages of PTFE, HP-PFA, and FEP hoses over stainless steel pipes
- Unlike stainless steel, the risk of biofilm formation is very low
- No welded seams, resulting in fewer microbiological weak points and extremely low extractables
- No sight glasses required, as translucent tubing makes process media visible
- Greater flexibility for plant retrofits and new generations
- No metal ions
- Reduced cleaning and maintenance requirements (CIP)
- Reduced contamination risks due to homogeneous inner surfaces
- Faster installation and easier validation
FEP Tubing Application Example: Filling Generic Drugs
Manufacturer of plastic tubing for the filling of pharmaceuticals and generic drugs
Every cleanroom and laboratory application has different requirements regarding bend radius, air volume, pressure conditions, temperature behavior, hygiene, and integration with existing systems. When filling pharmaceuticals or generic drugs, fluids must be precisely and reliably conveyed to the filling point under hygienically controlled conditions. FEP-based hose solutions from APT, a subsidiary of the Masterflex Group, stand out in this context due to their chemical resistance, transparency, and ease of integration into sensitive filling systems—qualities that are particularly relevant in pharmaceutical packaging and filling environments.
Connecting Tanks, Modules, and Dosing Points
Connecting Tanks, Modules, and Dosing Points—PTFE Tubing and More
Wherever tanks, dosing modules, analysis points, or transfer stations are connected to one another, hose systems with high adaptability and reliable fluid handling are required. PTFE and PFA hoses support such applications thanks to their versatility in complex fluid systems within the chemical and pharmaceutical industries. Furthermore, PTFE hoses—that is, extruded hoses without a metal spiral—impress with their extremely low coefficient of friction and high mechanical strength at high temperatures.
Cleanroom Hose Systems - Fluoropolymer Solutions for Sensitive High-End Applications
With Teflon™ Diamond—High-Purity PFA Tubing for High-End Applications
APT, a valued member of the Masterflex Group, develops customized high-purity fluoropolymer solutions. PFA tubing is characterized by its high chemical resistance, purity, and temperature stability. They are used in fields such as the chemical, pharmaceutical, semiconductor, and laboratory industries, where reliable materials are crucial. APT offers a wide range of PFA tubing that is precision-manufactured and optimized for use in demanding processes. APT distinguishes between two categories of PFA tubing: Standard PFA tubing offers the highest chemical resistance, purity, and temperature stability and is ideal for demanding applications in the chemical, pharmaceutical, semiconductor, and laboratory sectors. High-purity PFA tubing is designed for critical processes with the highest purity requirements, complies with the SEMI F57-0301 standard, and is used in particular in the semiconductor, photovoltaic, pharmaceutical, and biotechnology industries.
Hose Systems for Temperature-Controlled Supply in Cooling and Auxiliary Processes
Hoses for Controlled Fluid Transport in the Biopharmaceutical Industry
In temperature-controlled auxiliary processes, cooling circuits, or fluid-based supply systems, media must be transported continuously under controlled conditions. PTFE and PFA hoses for the chemical and pharmaceutical industries are suitable for such applications when thermal stability, chemical resistance, and long-term, stable performance are required.
Consulting and Development for Custom Hose Systems
APT’s fluoropolymer hoses are synonymous with the highest purity, excellent chemical resistance, and exceptional temperature stability. Using state-of-the-art extrusion technology, APT manufactures hoses from high-quality materials such as PTFE, PFA, FEP, ETFE, ECTFE, PVDF, and THV—precisely tailored to the requirements of a wide range of industries. In biopharmaceutical and pharmaceutical applications, tubing systems must not only be technically capable but also designed to meet regulatory requirements. PTFE and PFA tubing should therefore be evaluated in terms of purity, chemical compatibility, temperature resistance, documentation, and application-specific compliance.
It is crucial that the hose system (customization options are also available) can be reliably integrated into sensitive processes and supports both product quality and process reliability in the long term. Especially in chemical and pharmaceutical environments, a material- and application-specific design is therefore a key success factor.
The requirements for hose systems in biopharmaceuticals, fluid systems, and storage and cooling systems are high and often highly specific. That is why the Masterflex Group supports its customers from requirements analysis through material selection to the development of customer-specific system solutions. This results in safe hose solutions for the chemical and pharmaceutical industries that not only excel in terms of chemical and thermal performance but also function reliably in complex plant environments and can be seamlessly integrated into existing processes.
Specialized Solutions: Fluoropolymer Hoses—APT Product Catalog
Hoses Are Better Than Stainless Steel Piping for the Food, Pharmaceutical, and Biotech Industries
Before a product—such as a vaccine, a tablet, a dairy product, or a microchip—is completed, it typically goes through numerous process steps in complex industrial facilities. The journey takes the product through kilometers of tubing and piping systems with many connection points—from tank farms to reactors and fermenters, all the way to downstream processing. Pumps move the fluid streams, valves control them precisely, while sensitive sensors monitor the processes. In unit operations and process equipment, the media are further processed until the final product is finally ready for sterile filling or controlled dispensing. For pure performance, we support our customers as a reliable supplier and development partner throughout the entire value chain.
Hoses for the Food and Pharmaceutical Industries – Your Point of Contact
FDA-approved food-grade plastic tubing
Do you manufacture products or build equipment for the food industry? Masterflex Group develops FDA-compliant hose and connection solutions for demanding processes in the food and pharmaceutical industries. Whether in food manufacturing and processing, in filling systems, or in pharmaceutical production environments: Our food-grade hoses stand for quality, safety, and technical performance.
Air Distribution and Supply Applications
In the pharmaceutical industry, plastic tubing is used in cleanroom technology, for controlled airflow in filling systems, isolators, sterile areas, and exhaust and ventilation systems. It protects production processes from particles and contamination and supplies fresh air to the plant, laboratories, and employees.
Tablet, Powder, and Capsule Production
Pharmaceutical products such as capsules or tablets must be handled and transported with particular care. When active ingredients are used in pharmaceutical production to create precisely dosed tablets, capsules, or liquid medications, every step of the process must function accurately, hygienically, and with absolute reliability.
Frequently Asked Questions About Masterflex Group PTFE, FEP, and PFA Hose Solutions
Can PTFE and PFA tubing be marked or laser-engraved?
Yes, we offer laser-marked fluoropolymer tubing with continuous marking. While hoses made of engineering plastics such as PE or PA are typically marked, this is often not done when fluoropolymers are used, as conventional printing methods simply do not adhere to fluoropolymers. A new laser marking technology now enables marking with impressively high quality. In terms of the printed image, not only text but also logos and safety markings can be printed with razor-sharp clarity.
What are the manufacturing processes used for your fluoropolymer hoses?
APT utilizes state-of-the-art manufacturing equipment to perform conventional extrusion, co-extrusion, and paste extrusion of PTFE, enabling the production of high-precision, application-specific tubing solutions with exceptional dimensional accuracy and functionality.
What are PTFE, FEP, and PFA hoses?
PTFE, FEP, and PFA hoses are high-performance plastic hoses made of fluoropolymers that are characterized by high chemical resistance, temperature resistance, and exceptional purity, making them ideal for demanding media and process applications. Our specialist within the Masterflex Group is APT, based in Düsseldorf.
For which applications are PTFE or PFA hoses suitable in the pharmaceutical industry?
PTFE and PFA tubing is particularly well-suited in the pharmaceutical industry for high-purity, chemically aggressive, and temperature-sensitive media in applications such as fluid transfer, filling, bioprocesses, CIP/SIP cleaning, analytical and sterile production environments, as well as in single-use systems and pump, valve, and dosing lines, or in the high-purity semiconductor front-end.
What are the advantages of PFA tubing?
PFA tubing offers, above all, very high chemical resistance, high purity, temperature stability, and a long service life, making it ideally suited for demanding processes in the chemical, pharmaceutical, semiconductor, and laboratory technology industries. APT distinguishes between standard PFA tubing, designed to meet the highest standards of reliability and durability, and high-purity PFA tubing with an exceptionally low concentration of extractable substances in accordance with SEMI F57-0301, intended for highly critical applications in the semiconductor, photovoltaic, pharmaceutical, and biotechnology industries.
When are FEP hoses the right solution?
FEP tubing is ideal for chemical and pharmaceutical applications where transparency, controlled fluid flow, and easy integration into systems are required. It is frequently used in applications where process visibility and clean handling are important.
What is the minimum diameter for APT FEP hoses?
APT manufactures FEP tubing ranging from a minimum inner diameter of 0.10 mm to a maximum outer diameter of 100 mm. In addition to a wide range of standard sizes that we keep in stock, we can produce virtually any custom size; upon request, we can also color the tubing according to the RAL color palette.
When is a PTFE hose recommended?
A PTFE hose is particularly recommended for applications involving high chemical and thermal stress. For example, in a production laboratory. When media are corrosive or processes operate under demanding temperature conditions, PTFE provides a particularly durable material base.
Is it possible to get custom PTFE hoses?
APT manufactures PTFE tubing ranging from a minimum inner diameter of 0.30 mm to a maximum outer diameter of 20 mm. In addition to a wide range of standard sizes that we keep in stock, we can produce virtually any custom size, and upon request, we can color them according to the RAL color palette.
Are there also customized special solutions?
Yes, we can develop custom solutions tailored to individual system requirements. This includes, for example, special connection solutions, customized geometries, specific material combinations, or complex fluid systems for research, development, and production.
What is the most important factor when it comes to hoses for fluid systems?
It always depends on the specific requirements. As a general rule, the most important factors for hoses used in fluid systems are chemical resistance, purity, pressure and temperature resistance, and consistently reliable and safe process performance.
Why are PTFE and PFA hoses suitable for metal-sensitive substances?
Because they can be designed for inert and media-compatible applications, thereby reducing the risk of interactions with sensitive substances. This makes them particularly attractive for sensitive chemical and pharmaceutical processes.
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